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Oxaceprol, also 4-hydroxy-N-acetyl-L-proline, is a medication and nutraceutical. It is the N-acetyl derivative of 4-hydroxy-L-proline, a naturally occurring amino acid. It acts as a well tolerated anti-inflammatory drug, which has similar efficacy to other NSAIDs (such as acetaminophen, naproxen and ibuprofen) but with significantly reduced immunosuppressant effects which are common to NSAIDs.

Oxaceprol may have medicinal potential as a natural, amino-acid based treatment for osteoarthritis, bone or joint related diseases, due to its anti-inflammatory and analgesic properties.