Agmatine is a naturally occurring alkaloid, and a metabolite of the amino acid L-arginine. Once consumed, arginine will decarboxylate into agmatine during first-pass metabolism (just as tryptophan decarboxylates into tryptamine). Agmatine has many important pharmacological and biological effects in humans. It acts as an NMDA antagonist (in a manner similar to magnesium), an imidazoline agonist , and a 5HT2A and 5HT3 receptor antagonist, indicating possible antiemetic properties (similar to ondansetron). It also has shown possible analgesic activity in rat studies . This compound is NOT intended for human consumption, and is strictly for laboratory reagent or forensic analysis purposes ONLY. Available as the sulfate salt.
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 – https://www.ncbi.nlm.nih.gov/pubmed/7906055
 – https://www.ncbi.nlm.nih.gov/pubmed/15857629