L-aceglutamide, also known as N-acetyl-L-glutamine or neuramina, is an amino acid and stimulant/nootropic. It is most closely related to L-theanine, L-glutamine and L-glutamic acid.
Aceglutamide is a naturally occurring amino acid, and is a known metabolite of the essential amino acid glutamine, and is involved in the glutamine metabolic pathways. It is a more active form of glutamine, with improved bioavailability over glutamine. Due to enhanced oral potency and effects, aceglutamide can be used as a nutritional supplement as a source of glutamine.
L-aceglutamide may also have medicinal effects as a treatment for dementia, Alzheimer’s or cerebral trauma (such as infarction or ischemia arising from a stroke). It is also prescribed occasionally as a psychostimulant in the treatment of mental health disorders, under the brand name Neuramina. It may also be used as an NSAID (non-steroidal anti-inflammatory drug), or as a moderate analgesic (pain-relieving drug).
L-aceglutamide is marketed in China as a medicinal treatment called Guhong injection, where it is combined with safflower extract (Carthamus tinctorius) to treat cerebral trauma or diseases such as MCI (mild cognitive impairment) or Alzheimer’s. The combination of aceglutamide and safflower is said to enhance its medicinal effects.
This compound is NOT for human consumption and is strictly for research purposes ONLY. Available as the free acid.